It highlights new biocompatibility issues, metrics, and statistics as well as new legislation for intellectual property. Divided A practical road map to the key families of biomaterials and their potential applications in clinical therapeutics, Introduction to Biomaterials, Second Edition follows the entire path of development from theory to lab to practical application. Divided into four sections Biology, Biomechanics, Biomaterials Interactions; Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property; Biomaterials Compositions; and Biomaterials Applications , this dramatically revised edition includes both new and revised chapters on cells, tissues, and signaling molecules in wound healing cascades, as well as two revised chapters on standardized materials testing with in vitro and in vivo paradigms consistent with regulatory guidelines. Emphasizing biocompatibility at the biomaterial-host interface, it investigates cell-cell interactions, cell-signaling and the inflammatory and complement cascades, specific interactions of protein-adsorbed materials, and other inherent biological constraints including solid-liquid interfaces, diffusion, and protein types.
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Jeffrey O. Hollinger graduated from Hofstra University in and received a dental degree and PhD from the University of Maryland in and , respectively.
In addition, he completed a dental residency program and craniofacial fellowship in the U. Army Dental Corps. Since , Dr. Hollinger has been a tenured professor at Carnegie Mellon University CMU in the departments of biomedical engineering and biological sciences. From to , he was a tenured professor at the Oregon Health Sciences University in the departments of surgery and developmental biology, and he directed the Northwest Wound Healing Center.
In Dr. Hollinger retired from the U. Army as a colonel after serving 20 years of active duty. He has over 35 years of experience in bone regeneration using biological factors, biomaterials, and preclinical animal models. Hollinger has received numerous federal grants as the principal investigator NIH, NSF, DoD, and NIST focusing on applied and fundamental sciences for bone regeneration and is engaged with several industrial groups emphasizing bone regenerative therapeutics, as well as serving on corporate boards.
Hollinger has several patents and has licensed technology developed in his lab. He received the prestigious Clemson Award in biomaterials in He has over peer-reviewed publications, abstracts, book chapters, and books. Macri and R. Clark Osseous Wound Healing, A. Nawab, M. Wong, D. Kwak, L. Schutte, A. Sharma, and J. Guo, P. Alvarez, and Y. Harbers and D. Grainger Host Response to Biomaterials, D. Holt and D. LeDuc, L. Gonzalez, B. Rauck, and Y. Kim, A. Srinivasan, and J. Raut, T.
Patterson, J. Wenke, J. Hollinger, and G. Rubin, J. McKlveen, A. Fultz, and M. Hart, M. Citron, A. Loewen-Rodriguez, and J. Douglas, Esq. Haarer, B. Inskeep, and K. Tawil and B. Wu The Poly -esters , D. Jamiolkowski and E. Dormier Biomedical Polyurethanes, M. Szycher Polymers Derived from l-Tyrosine, J. Kohn, A. Darr, and J. Schut Poly propylene Fumarate , X. Shi, A. Henslee, D. Yoon, F. Kasper, and A.
Mikos Hyaluronan, J. Brekke, G. Rutowski, and K. Rauh, M. Dornish, R. Street, and A. Reddi and P. Alvarez-Urena Polyphosphazenes, L. Nair, Y. Khan, and C. Laurencin Biologically Active Glasses, H. Elgendy, D. Curtin, and A. Qin and D. Crumlett, B. Singleton, S. Oh, and J. Powell and S. Loo and K. Wang, L. Lu, B. Currier, and M.
Yaszemski Bone and Biomaterials, S. Nukavarapu, J. Wallace, H. Elgendy, J. Lieberman, and C. Lee and J. Kokai, L. Santiago, and K. Freeman, V. Walters, and A. Baraniak and W. Wagner Index.
An Introduction to Biomaterials
Macri and R. Clark Osseous Wound Healing, A. Nawab, M. Wong, D. Kwak, L. Schutte, A.
AN INTRODUCTION TO BIOMATERIALS HOLLINGER PDF