Are You Confident of the Diagnosis? What you should be alert for in the history Erythema induratum also referred to as erythema induratum of Bazin EIB or nodular vasculitis is a chronic nodular skin disease that is thought to represent a hypersensitivity response to Mycobacterium tuberculosis or its antigens. Erythema induratum classically presents during early adolescence and peri-menopause as subcutaneous poorly defined erythematous plaques and tender violaceous nodules. The disease preferentially affects the posterior and anterolateral aspects of the lower legs of women; however it can occur in other locations as well as in men and children. Patients may describe a prolonged history of recurrent episodes over years or decades with new crops of lesions appearing often unpredictably. Typically, lesions are tender but nonpruritic and may be precipitated by cold weather.

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Figura 4 Eritema indurado vasculitis nodular. Figura 5 Eritema indurado vasculitis nodular. A Paniculitis principalmente lobular con vasculitis. Los casos asociados a TB se clasifican como una de las formas verdaderas de "tuberculides". El dolor es variable, pero generalmente no es insoportable si es que existe. Las lesiones cicatrizadas pueden dejar cicatrices. Las asociaciones de enfermedades distintas de la TB son mucho menos comunes pero han sido documentadas en los informes de casos. La vasculitis no siempre se observa.

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Eritema induratum

Erythema induratum is a rare condition that classically produces painful, firm and sometimes ulcerated nodules on the lower legs in association with tuberculosis TB. Classification In the term nodular vasculitis was coined to describe chronic inflammatory nodules of the legs that showed histopathological changes similar to those of erythema induratum, but without an association with TB. The vasculitis is of the larger vessels with panniculitis - an inflammation involving subcutaneous fat and occasionally muscle, with or without vasculitis. Erythema induratum and nodular vasculitis had been seen as the same disease for many years but nodular vasculitis is now considered to be a multifactorial syndrome of lobular panniculitis in which tuberculosis may or may not be one of the various aetiologies. It is now classified as: Erythema induratum of Bazin type - associated with TB. Erythema induratum or nodular vasculitis of Whitfield type - no association with TB. Pathophysiology The disease or diseases represent an inflammatory reaction.


Erythema Induratum

Lokalisation Unterschenkel, beugeseitig. Extrem chronischer, bzw. Ratzinger et al. Wenige Plasmazellen.


Erythema Induratum (Erythema induratum of Bazin, Nodular Vasculitis)



Erythema induratum


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